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Assay Detail

CHEMBL5615853

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Activation of Myosin ATPase activity in bovine Cardio-myofibril
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bos taurus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

A comprehensive review of new small molecule drugs approved by the FDA in 2022: Advance and prospect.
Bai YR, Yang X, Chen KT, Cuan XD, Zhang YD, Zhou L, Yang L, Liu HM, Yuan S.
Eur J Med Chem (2024) 277 : 116759 -116759
PubMed 39137454 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.15 6.15

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4297517 MAVACAMTEN 4.0 1 6.15

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4297517 MAVACAMTEN EC50 = 711.0 nM 6.15