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Assay Detail

CHEMBL5615857

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of IDH1 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Isocitrate dehydrogenase [NADP] cytoplasmic (CHEMBL2007625)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

A comprehensive review of new small molecule drugs approved by the FDA in 2022: Advance and prospect.
Bai YR, Yang X, Chen KT, Cuan XD, Zhang YD, Zhou L, Yang L, Liu HM, Yuan S.
Eur J Med Chem (2024) 277 : 116759 -116759
PubMed 39137454 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.68 7.68

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4297610 OLUTASIDENIB 4.0 1 7.68

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4297610 OLUTASIDENIB IC50 = 21.0 nM 7.68