Assay Detail
Binding
CHEMBL5615863
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of OX2R (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A comprehensive review of new small molecule drugs approved by the FDA in 2022: Advance and prospect.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.82 | 8.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4297590 | DARIDOREXANT | 4.0 | 1 | 8.77 |
| CHEMBL1083659 | SUVOREXANT | 4.0 | 1 | 6.86 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4297590 | DARIDOREXANT | IC50 | = | 1.7 | nM | 8.77 |
| CHEMBL1083659 | SUVOREXANT | IC50 | = | 138.0 | nM | 6.86 |