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Assay Detail

CHEMBL5616668

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to biotin-labeled cardiolipin (unknown origin) by biolayer interferometry
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Not specified
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Discovery of novel dihydropyrrolidone-thiadiazole compound crosstalk between the YycG/F two-component regulatory pathway and cell membrane homeostasis to combat methicillin-resistant Staphylococcus aureus.
Xiong Y, Wang R, Zheng J, Fang D, He P, Liu S, Lin Z, Chen X, Chen C, Shang Y, Yu Z, Liu X, Han S.
Eur J Med Chem (2024) 277 : 116770 -116770
PubMed 39208742 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 4.36 4.36

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5618879 1 4.36

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5618879 Kd = 44100.0 nM 4.36