Assay Detail
Binding
CHEMBL5620480
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of KDR (unknown origin) using peptide as substrate incubated for 90 mins in presence of ATP by HTRF method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Vascular endothelial growth factor receptor 2 (CHEMBL279) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
CSF1R inhibitors are emerging immunotherapeutic drugs for cancer treatment.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.82 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1614710 | OSI-930 | 1.0 | 1 | 7.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1614710 | OSI-930 | IC50 | = | 15.0 | nM | 7.82 |