Assay Detail
Binding
CHEMBL5620538
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human PDE4 catalytic domain expressed in Escherichia coli
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Advances in the development of phosphodiesterase 7 inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.24 | 8.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5625140 | — | — | 1 | 8.64 |
| CHEMBL503012 | — | — | 1 | 6.89 |
| CHEMBL5630984 | — | — | 1 | 6.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5625140 | — | IC50 | = | 2.3 | nM | 8.64 |
| CHEMBL503012 | — | IC50 | = | 130.0 | nM | 6.89 |
| CHEMBL5630984 | — | IC50 | = | 630.0 | nM | 6.20 |