Assay Detail
Binding
CHEMBL5620540
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PDE7A (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
High affinity 3',5'-cyclic-AMP phosphodiesterase 7A (CHEMBL3012) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Advances in the development of phosphodiesterase 7 inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.39 | 9.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4297384 | GSK-356278 | 1.0 | 1 | 9.12 |
| CHEMBL5625125 | — | — | 1 | 7.73 |
| CHEMBL451589 | — | — | 1 | 5.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4297384 | GSK-356278 | IC50 | = | 0.76 | nM | 9.12 |
| CHEMBL5625125 | — | IC50 | = | 18.6 | nM | 7.73 |
| CHEMBL451589 | — | IC50 | = | 4700.0 | nM | 5.33 |