Assay Detail
Binding
CHEMBL5620545
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PDE7 (unknown origin) by fluorescent based assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Advances in the development of phosphodiesterase 7 inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.50 | 7.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3646900 | — | — | 1 | 7.43 |
| CHEMBL3646893 | — | — | 1 | 7.41 |
| CHEMBL3646899 | — | — | 1 | 7.34 |
| CHEMBL5630169 | — | — | 1 | 6.42 |
| CHEMBL1699472 | — | — | 1 | 5.99 |
| CHEMBL5613951 | — | — | 1 | 5.80 |
| CHEMBL275084 | ISOBUTYLMETHYLXANTHINE | — | 1 | 5.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3646900 | — | IC50 | = | 37.0 | nM | 7.43 |
| CHEMBL3646893 | — | IC50 | = | 39.0 | nM | 7.41 |
| CHEMBL3646899 | — | IC50 | = | 46.0 | nM | 7.34 |
| CHEMBL5630169 | — | IC50 | = | 380.0 | nM | 6.42 |
| CHEMBL1699472 | — | IC50 | = | 1020.0 | nM | 5.99 |
| CHEMBL5613951 | — | IC50 | = | 1590.0 | nM | 5.80 |
| CHEMBL275084 | ISOBUTYLMETHYLXANTHINE | IC50 | = | 8100.0 | nM | 5.09 |