Assay Detail
Binding
CHEMBL5620547
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Inhibition of PDE4 (unknown origin) by fluorescent based assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Advances in the development of phosphodiesterase 7 inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.00 | 7.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3403346 | — | — | 1 | 7.34 |
| CHEMBL1911416 | — | — | 1 | 6.42 |
| CHEMBL5629944 | — | — | 1 | 5.85 |
| CHEMBL1236215 | — | — | 1 | 5.46 |
| CHEMBL5625119 | — | — | 1 | 4.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3403346 | — | IC50 | = | 46.0 | nM | 7.34 |
| CHEMBL1911416 | — | IC50 | = | 380.0 | nM | 6.42 |
| CHEMBL5629944 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL1236215 | — | IC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL5625119 | — | IC50 | = | 11900.0 | nM | 4.92 |