Assay Detail
Functional
CHEMBL5620879
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against adefovir-resistant HBV infected in human HepG2 cells assessed as reduction in of intracellular HBV DNA incubated for 5 days by Southern blotting analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepatitis B virus |
| Cell Type | HepG2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Advancing beyond reverse transcriptase inhibitors: The new era of hepatitis B polymerase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.18 | 6.18 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL78101 | — | — | 1 | 6.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL78101 | — | EC50 | = | 660.0 | nM | 6.18 |