Assay Detail
Functional
CHEMBL5622701
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Antiviral activity against CHIKV infected african green monkey Vero cells assessed as inhibition of virus induced cytopathic effect measured after 48 hrs
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Chikungunya virus |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design, synthesis, antiviral evaluation, and In silico studies of acrylamides targeting nsP2 from Chikungunya virus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 4.73 | 5.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5630521 | — | — | 1 | 5.28 |
| CHEMBL5630381 | — | — | 1 | 4.59 |
| CHEMBL5624692 | — | — | 1 | 4.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5630521 | — | EC50 | = | 5200.0 | nM | 5.28 |
| CHEMBL5630381 | — | EC50 | = | 25900.0 | nM | 4.59 |
| CHEMBL5624692 | — | EC50 | = | 47900.0 | nM | 4.32 |