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Assay Detail

CHEMBL5625550

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Toxicity
Cytotoxicity against mouse HL-1 cells assessed as cell viability incubated for 24 hrs by CytoTox-Glo luminescence assay relative to control
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Toxicity
Organism Mus musculus
Cell Type HL-1
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Pharmacological activity and mechanism of pyrazines.
Hou W, Dai W, Huang H, Liu SL, Liu J, Huang LJ, Huang XH, Zeng JL, Gan ZW, Zhang ZY, Lan JX.
Eur J Med Chem (2023) 258 : 115544 -115544
PubMed 37300915 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.84 5.84

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL396985 1 5.84

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL396985 IC50 = 1430.0 nM 5.84