Assay Detail
Binding
CHEMBL5626149
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of KDR (unknown origin) using peptide substrate incubated for 90 mins in presence of ATP by HTRF method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Vascular endothelial growth factor receptor 2 (CHEMBL279) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Quinazoline-based VEGFR-2 inhibitors as potential anti-angiogenic agents: A contemporary perspective of SAR and molecular docking studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.33 | 8.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL440727 | — | — | 1 | 8.64 |
| CHEMBL3775169 | — | — | 1 | 8.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL440727 | — | IC50 | = | 2.3 | nM | 8.64 |
| CHEMBL3775169 | — | IC50 | = | 9.5 | nM | 8.02 |