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Assay Detail

CHEMBL5626182

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Functional
Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MCF7
Confidence 1 — Organism
Curated By Autocuration

Target

MCF7 (CHEMBL387)
Type CELL-LINE
Organism Homo sapiens

Publication

Quinazoline-based VEGFR-2 inhibitors as potential anti-angiogenic agents: A contemporary perspective of SAR and molecular docking studies.
Moradi M, Mousavi A, Emamgholipour Z, Giovannini J, Moghimi S, Peytam F, Honarmand A, Bach S, Foroumadi A.
Eur J Med Chem (2023) 259 : 115626 -115626
PubMed 37453330 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.67 5.67

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5632719 1 5.67

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5632719 IC50 = 2120.0 nM 5.67