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Assay Detail

CHEMBL5626249

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Binding
Inhibition of Kv1.2 (unknown origin) expressed in Xenopus laevis Oocyte cells by electrophysiological recording
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type Oocyte
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Potassium voltage-gated channel subfamily A member 2 (CHEMBL2086)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Immunosuppressive effects of new thiophene-based K<sub>V</sub>1.3 inhibitors.
Gubič Š, Montalbano A, Sala C, Becchetti A, Hendrickx LA, Van Theemsche KM, Pinheiro-Junior EL, Altadonna GC, Peigneur S, Ilaš J, Labro AJ, Pardo LA, Tytgat J, Tomašič T, Arcangeli A, Peterlin Mašič L.
Eur J Med Chem (2023) 259 : 115561 -115561
PubMed 37454520 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.51 6.51

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5631442 1 6.51

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5631442 IC50 = 308.0 nM 6.51