Assay Detail
Functional
CHEMBL5626499
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Cytotoxicity against human MCF7 cells incubated for 72 hrs by SRB assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Targeted theranostics: Near-infrared triterpenoic acid-rhodamine conjugates as prerequisites for precise cancer diagnosis and therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 6.83 | 7.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5632064 | — | — | 1 | 7.89 |
| CHEMBL6067727 | — | — | 1 | 7.70 |
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 7.47 |
| CHEMBL5632695 | — | — | 1 | 7.11 |
| CHEMBL5632981 | — | — | 1 | 6.83 |
| CHEMBL5632266 | — | — | 1 | 6.47 |
| CHEMBL5633595 | — | — | 1 | 6.38 |
| CHEMBL5632328 | — | — | 1 | 6.30 |
| CHEMBL5633187 | — | — | 1 | 6.28 |
| CHEMBL5631272 | — | — | 1 | 5.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5632064 | — | IC50 | = | 12.9 | nM | 7.89 |
| CHEMBL6067727 | — | IC50 | = | 19.9 | nM | 7.70 |
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 34.2 | nM | 7.47 |
| CHEMBL5632695 | — | IC50 | = | 77.6 | nM | 7.11 |
| CHEMBL5632981 | — | IC50 | = | 147.4 | nM | 6.83 |
| CHEMBL5632266 | — | IC50 | = | 336.9 | nM | 6.47 |
| CHEMBL5633595 | — | IC50 | = | 418.0 | nM | 6.38 |
| CHEMBL5632328 | — | IC50 | = | 495.8 | nM | 6.30 |
| CHEMBL5633187 | — | IC50 | = | 530.4 | nM | 6.28 |
| CHEMBL5631272 | — | IC50 | = | 1273.0 | nM | 5.89 |