Assay Detail
Toxicity
CHEMBL5629550
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Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Toxicity |
| Organism | Homo sapiens |
| Cell Type | MRC5 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic effects of kinetin riboside and its selected analogues on cancer cell lines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.55 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5633381 | — | — | 1 | 6.00 |
| CHEMBL406643 | — | — | 1 | 5.68 |
| CHEMBL411066 | KINETIN RIBOSIDE | — | 1 | 5.60 |
| CHEMBL5632198 | — | — | 1 | 4.93 |
| CHEMBL5632256 | — | — | 1 | - |
| CHEMBL5632167 | — | — | 1 | - |
| CHEMBL5632437 | — | — | 1 | - |
| CHEMBL5629964 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5633381 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL406643 | — | IC50 | = | 2100.0 | nM | 5.68 |
| CHEMBL411066 | KINETIN RIBOSIDE | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL5632198 | — | IC50 | = | 11700.0 | nM | 4.93 |
| CHEMBL5632256 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL5632167 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL5632437 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL5629964 | — | IC50 | > | 100000.0 | nM | - |