Assay Detail
Binding
CHEMBL5629779
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of COX-2 (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Improved synthesis, molecular modeling and anti-inflammatory activity of new fluorinated dihydrofurano-naphthoquinone compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 5.89 | 6.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL256147 | TILARGININE | 3.0 | 1 | 6.62 |
| CHEMBL5631898 | — | — | 1 | 5.73 |
| CHEMBL5632670 | — | — | 1 | 5.70 |
| CHEMBL5633552 | — | — | 1 | 5.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL256147 | TILARGININE | Ki | = | 240.0 | nM | 6.62 |
| CHEMBL5631898 | — | Ki | = | 1860.0 | nM | 5.73 |
| CHEMBL5632670 | — | Ki | = | 1990.0 | nM | 5.70 |
| CHEMBL5633552 | — | Ki | = | 3080.0 | nM | 5.51 |