Assay Detail
Binding
CHEMBL5634352
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Binding affinity to HIV1 Gag assessed as dissociation constant
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Human immunodeficiency virus type 1 Gag protein (CHEMBL3556) ↗| Type | SINGLE PROTEIN |
| Organism | Human immunodeficiency virus 1 |
Publication
Fluorine in anti-HIV drugs approved by FDA from 1981 to 2023.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 8.79 | 8.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4594438 | LENACAPAVIR | 4.0 | 1 | 8.96 |
| CHEMBL5641856 | — | — | 1 | 8.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4594438 | LENACAPAVIR | Kd | = | 1.1 | nM | 8.96 |
| CHEMBL5641856 | — | Kd | = | 2.4 | nM | 8.62 |