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Assay Detail

CHEMBL5634384

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human KM12 cells assessed as reduction in cell viability after 48 hrs by SRB assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type KM12
Confidence 1 — Organism
Curated By Autocuration

Target

KM12 (CHEMBL614709)
Type CELL-LINE
Organism Homo sapiens

Publication

Recent advances in the discovery of tropomyosin receptor kinases TRKs inhibitors: A mini review.
El-Nassan HB, Al-Qadhi MA.
Eur J Med Chem (2023) 258 : 115618 -115618
PubMed 37413881 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.09 7.09

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4849505 1 7.09

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4849505 IC50 = 82.0 nM 7.09