Assay Detail
Functional
CHEMBL5634705
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human MKN-1 cells assessed as reduction in cell viability measured after 48 hrs by 48 hrs by CCK-8 assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MKN-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent advances in the development of inhibitors targeting KRAS-G12C and its related pathways.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.34 | 7.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5208088 | — | — | 1 | 7.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5208088 | — | IC50 | = | 46.0 | nM | 7.34 |