Assay Detail

CHEMBL5635262

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding

Inhibition of His-tagged recombinant human NAE expressed in Escherichia coli (BL21) by HTRF assay

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Micafungin: A promising inhibitor of UBE2M in cancer cell growth suppression.

Mamun MAA, Liu S, Zhao L, Zhao L, Li ZR, Shen D, Zheng Y, Zheng YC, Liu HM.
Eur J Med Chem (2023) 260 : 115732 -115732
PubMed 37651876 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	8.24	8.24

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL1231160	PEVONEDISTAT	3.0	1	8.24

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL1231160	PEVONEDISTAT	IC50	=	5.8	nM	8.24