Assay Detail
Functional
CHEMBL5635754
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Cytotoxicity against human RPMI-8226 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | RPMI-8226 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent advances in small molecule and peptide inhibitors of glucose-regulated protein 78 for cancer therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.74 | 4.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL288542 | — | — | 1 | 4.90 |
| CHEMBL560141 | — | — | 1 | 4.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL288542 | — | IC50 | = | 12600.0 | nM | 4.90 |
| CHEMBL560141 | — | IC50 | = | 27200.0 | nM | 4.57 |