Assay Detail
Functional
CHEMBL5635757
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Cytotoxicity against human HL60/MX2 assessed as inhibition of cell growth incubated for 72 hrs by SRB assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL60/MX2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent advances in small molecule and peptide inhibitors of glucose-regulated protein 78 for cancer therapy.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.42 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4174126 | — | — | 1 | 7.00 |
| CHEMBL4167750 | — | — | 1 | 6.77 |
| CHEMBL4167314 | — | — | 1 | 6.72 |
| CHEMBL2147890 | — | — | 1 | 6.21 |
| CHEMBL1819010 | — | — | 1 | 6.19 |
| CHEMBL561602 | — | — | 1 | 5.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4174126 | — | IC50 | = | 99.0 | nM | 7.00 |
| CHEMBL4167750 | — | IC50 | = | 170.0 | nM | 6.77 |
| CHEMBL4167314 | — | IC50 | = | 190.0 | nM | 6.72 |
| CHEMBL2147890 | — | IC50 | = | 620.0 | nM | 6.21 |
| CHEMBL1819010 | — | IC50 | = | 640.0 | nM | 6.19 |
| CHEMBL561602 | — | IC50 | = | 2500.0 | nM | 5.60 |