Assay Detail

CHEMBL5636738

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Functional

Inhibition of human whole blood CD69 B cell activation

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

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Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	CD69 B cell
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Synthesis and application of small molecules approved for the treatment of lymphoma.

Guo YY, Zhang JY, Sun JF, Nie P, Gao H.
Eur J Med Chem (2023) 261 : 115835 -115835
PubMed 37801827 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	1	8.10	8.10

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL3707348	ACALABRUTINIB	4.0	1	8.10

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL3707348	ACALABRUTINIB	EC50	=	8.0	nM	8.10