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Assay Detail

CHEMBL5648235

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human HeLa cells expressing H2B-YFP assessed as inhibition of cell proliferation incubated for 5 days
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HeLa
Confidence 1 — Organism
Curated By Autocuration

Target

HeLa (CHEMBL399)
Type CELL-LINE
Organism Homo sapiens

Publication

Molecular basis underlying resistance to Mps1/TTK inhibitors.
Koch A, Maia A, Janssen A, Medema RH.
Oncogene (2016) 35 : 2518 -2528
PubMed 26364596 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.55 7.55

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4757879 1 7.55

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4757879 IC50 = 28.4 nM 7.55