Assay Detail
Binding
CHEMBL5651065
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human CCT5 incubated for 45 mins by Kinobead based pull down assay
4
Total Activities
2
Compounds Tested
2
Activity Types
2
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
T-complex protein 1 subunit epsilon (CHEMBL4295766) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 8.48 | 9.67 |
| ED50 | 2 | 8.48 | 9.67 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| EFO_ID | EFO_ID | - | — | MONDO:0004992 |
| EFO_TERM | EFO_TERM | - | — | cancer |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3752910 | — | — | 2 | 9.67 |
| CHEMBL5653589 | — | — | 2 | 7.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3752910 | — | Kd | = | 0.216 | nM | 9.67 |
| CHEMBL3752910 | — | ED50 | = | 0.216 | nM | 9.67 |
| CHEMBL5653589 | — | Kd | = | 51.64 | nM | 7.29 |
| CHEMBL5653589 | — | ED50 | = | 51.64 | nM | 7.29 |