Assay Detail
Binding
CHEMBL5652477
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Binding affinity to human SLIRP incubated for 45 mins by Kinobead based pull down assay
2
Total Activities
1
Compounds Tested
2
Activity Types
2
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
SRA stem-loop-interacting RNA-binding protein, mitochondrial (CHEMBL6066420) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 9.67 | 9.67 |
| ED50 | 1 | 9.67 | 9.67 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| EFO_ID | EFO_ID | - | — | MONDO:0004992 |
| EFO_TERM | EFO_TERM | - | — | cancer |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5653589 | — | — | 2 | 9.67 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5653589 | — | Kd | = | 0.214 | nM | 9.67 |
| CHEMBL5653589 | — | ED50 | = | 0.214 | nM | 9.67 |