Assay Detail
Binding
CHEMBL5653984
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PKC (unknown origin) incubated for 30 mins in presence of ATP by Pep-Tag reagent based UV-laser densitometer analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
4
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.67 | 6.67 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| EFO_ID | EFO_ID | - | — | EFO:0000365 |
| EFO_ID | EFO_ID | - | — | MONDO:0018177 |
| EFO_TERM | EFO_TERM | - | — | colorectal adenocarcinoma |
| EFO_TERM | EFO_TERM | - | — | glioblastoma |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL16958 | STAUROSPORINONE | — | 1 | 6.67 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL16958 | STAUROSPORINONE | IC50 | = | 214.0 | nM | 6.67 |