Assay Detail
Functional
CHEMBL5680397
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human Rh41 cells assessed as inhibition of cell viability incubated for 72 hrs by 3H-thymidine incorporation assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Rh41 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
BMS-754807, a small molecule inhibitor of insulin-like growth factor-1R/IR.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.30 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL575448 | BMS-754807 | 2.0 | 1 | 8.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL575448 | BMS-754807 | IC50 | = | 5.0 | nM | 8.30 |