Assay Detail
Functional
CHEMBL5706549
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Antiproliferative activity against human COLO201 cells assessed as inhibition of cell viability measured for 6 to 7 days by cell titer glo assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | COLO 201 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
GSK1070916, a potent Aurora B/C kinase inhibitor with broad antitumor activity in tissue culture cells and human tumor xenograft models.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 8.70 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1090479 | GSK-1070916 | 1.0 | 1 | 8.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1090479 | GSK-1070916 | EC50 | = | 2.0 | nM | 8.70 |