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Assay Detail

CHEMBL5714399

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against human BXD-1425EPN cells assessed as reduction in cell viability incubated for 144 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type BXD-1425EPN
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Limitations of current <i>in vitro</i> models for testing the clinical potential of epigenetic inhibitors for treatment of pediatric ependymoma.
Rogers HA, Chapman R, Kings H, Allard J, Barron-Hastings J, Pajtler KW, Sill M, Pfister S, Grundy RG.
Oncotarget (2018) 9 : 36530 -36541
PubMed 30559935 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.40 6.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1201129 DECITABINE 4.0 1 6.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1201129 DECITABINE IC50 = 400.0 nM 6.40