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Assay Detail

CHEMBL5714925

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Anti-proliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MDA-MB-231
Confidence 1 — Organism
Curated By Autocuration

Target

MDA-MB-231 (CHEMBL400)
Type CELL-LINE
Organism Homo sapiens

Publication

Discovery of novel ATAD2 bromodomain inhibitors that trigger apoptosis and autophagy in breast cells by structure-based virtual screening.
Yao D, Zhang J, Wang J, Pan D, He Z.
J Enzyme Inhib Med Chem (2020) 35 : 713 -725
PubMed 32174193 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.98 5.98

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5074478 1 5.98

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5074478 IC50 = 1050.0 nM 5.98