Assay Detail

CHEMBL5715798

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Binding

Selectivity interaction (Enzymatic assay) EUB0002198aAD CASP14

ChEMBL ↗

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Target

Caspase-14 (CHEMBL5991) ↗

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Primary target Caspase-14

CHEMBL5991

Anchored from Assay target.

Protein identity Caspase-14

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Category	Selectivity assay
Confidence	9 — Direct single protein target
Curated By	Autocuration

Target

Caspase-14 (CHEMBL5991) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

Selectivity Literature for EUbOPEN Chemogenomic Library

EUbOPEN
(2024)
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.87	6.87

Assay Parameters

Parameter	Type	Value	Units	Text
Recommended concentration	Recommended concentration	1.0	uM	—

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL5715921	—	—	1	6.87

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL5715921	—	IC50	=	134.0	nM	6.87