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Assay Detail

CHEMBL5720974

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Binding
Inhibition of PI4KB (unknown origin) by membrane capture assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Phosphatidylinositol 4-kinase beta (CHEMBL3268)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Inhibition of Human Class I vs Class III Phosphatidylinositol 3'-Kinases.
Hassett MR, Sternberg AR, Roepe PD.
Biochemistry (2017) 56 : 4326 -4334
PubMed 28719179 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 6.56 7.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1229535 1 7.77
CHEMBL3781415 1 5.35

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1229535 EC50 = 17.0 nM 7.77
CHEMBL3781415 EC50 = 4430.0 nM 5.35