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Assay Detail

CHEMBL5723241

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Affinity Biochemical interaction: (enzymatic assay detecting released Coenzyme A) EUB0002242b FASN
1
Total Activities
1
Compounds Tested
1
Activity Types
3
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Category Affinity biochemical assay
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Fatty acid synthase (CHEMBL4158)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Affinity Biochemical Literature for EUbOPEN Chemogenomic Library
EUbOPEN
(2024)
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.11 8.11

Assay Parameters

Parameter Type Value Units Text
Mode of action Mode of action - Inhibitor
Protein family Protein family - Synthase
Recommended concentration Recommended concentration 1.0 uM

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3646801 1 8.11

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3646801 IC50 = 7.7 nM 8.11