Assay Detail
Functional
CHEMBL5723448
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Affinity On-target Cellular interaction: (Reporter gene assay (HEK293T cells)) EUB0001141a PPARD
1
Total Activities
1
Compounds Tested
1
Activity Types
3
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HEK-293T |
| Category | Affinity on-target cellular assay |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Peroxisome proliferator-activated receptor delta (CHEMBL3979) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Affinity On-target Cellular Literature for EUbOPEN Chemogenomic Library
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.80 | 6.80 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Mode of action | Mode of action | - | — | Agonist |
| Protein family | Protein family | - | — | Nuclear-receptor |
| Recommended concentration | Recommended concentration | 1.0 | uM | — |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL219586 | GW590735 | 2.0 | 1 | 6.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL219586 | GW590735 | EC50 | = | 160.0 | nM | 6.80 |