Assay Detail
Binding
CHEMBL5733424
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition Assay: The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening assay as known in the art.
9
Total Activities
3
Compounds Tested
3
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Methods to treat lymphoplasmacytic lymphoma
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.09 | 5.09 |
| kon | 3 | - | - |
| k_off | 3 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5950918 | — | — | 3 | 5.09 |
| CHEMBL5994443 | — | — | 3 | - |
| CHEMBL6014241 | — | — | 3 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5950918 | — | IC50 | = | 8210.0 | nM | 5.09 |
| CHEMBL5950918 | — | kon | = | - | — | - |
| CHEMBL5950918 | — | k_off | = | - | s-1 | - |
| CHEMBL5994443 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL5994443 | — | kon | = | - | — | - |
| CHEMBL5994443 | — | k_off | = | - | s-1 | - |
| CHEMBL6014241 | — | IC50 | > | 3330.0 | nM | - |
| CHEMBL6014241 | — | kon | = | - | — | - |
| CHEMBL6014241 | — | k_off | = | - | s-1 | - |