Assay Detail
Binding
CHEMBL5735302
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TBD: TBD
12
Total Activities
4
Compounds Tested
3
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
LXR agonists and uses thereof
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 7.48 | 7.62 |
| kon | 4 | - | - |
| k_off | 4 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL456237 | LXR-623 | 1.0 | 3 | 7.62 |
| CHEMBL5775096 | — | — | 3 | 7.60 |
| CHEMBL59030 | — | — | 3 | 7.40 |
| CHEMBL62136 | T091317 | — | 3 | 7.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL456237 | LXR-623 | EC50 | = | 24.0 | nM | 7.62 |
| CHEMBL5775096 | — | EC50 | = | 25.0 | nM | 7.60 |
| CHEMBL59030 | — | EC50 | = | 40.0 | nM | 7.40 |
| CHEMBL62136 | T091317 | EC50 | = | 50.0 | nM | 7.30 |
| CHEMBL59030 | — | kon | = | - | — | - |
| CHEMBL59030 | — | k_off | = | - | s-1 | - |
| CHEMBL5775096 | — | kon | = | - | — | - |
| CHEMBL5775096 | — | k_off | = | - | s-1 | - |
| CHEMBL62136 | T091317 | kon | = | - | — | - |
| CHEMBL62136 | T091317 | k_off | = | - | s-1 | - |
| CHEMBL456237 | LXR-623 | kon | = | - | — | - |
| CHEMBL456237 | LXR-623 | k_off | = | - | s-1 | - |