Assay Detail
Binding
CHEMBL5738779
Review assay metadata, readout intent, target linkage, and publication context from the same page.
TBD: TBD
150
Total Activities
50
Compounds Tested
3
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Compositions and methods for treating infections
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 50 | 7.80 | 8.87 |
| kon | 50 | - | - |
| k_off | 50 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL119 | TRIMETREXATE | 4.0 | 3 | 8.87 |
| CHEMBL5941951 | — | — | 3 | 8.70 |
| CHEMBL4468777 | FANOTAPRIM | 1.0 | 3 | 8.49 |
| CHEMBL5936551 | — | — | 3 | 8.46 |
| CHEMBL5985430 | — | — | 3 | 8.41 |
| CHEMBL5751279 | — | — | 3 | 8.38 |
| CHEMBL5796794 | — | — | 3 | 8.36 |
| CHEMBL4543226 | — | — | 3 | 8.35 |
| CHEMBL4573445 | — | — | 3 | 8.32 |
| CHEMBL6034917 | — | — | 3 | 8.25 |
| CHEMBL5883668 | — | — | 3 | 8.24 |
| CHEMBL5877082 | — | — | 3 | 8.23 |
| CHEMBL4464707 | — | — | 3 | 8.22 |
| CHEMBL5830010 | — | — | 3 | 8.21 |
| CHEMBL5806347 | — | — | 3 | 8.21 |
| CHEMBL5831279 | — | — | 3 | 8.19 |
| CHEMBL6014553 | — | — | 3 | 8.17 |
| CHEMBL6001741 | — | — | 3 | 8.16 |
| CHEMBL5806112 | — | — | 3 | 8.14 |
| CHEMBL5759188 | — | — | 3 | 8.14 |
| CHEMBL5857341 | — | — | 3 | 8.09 |
| CHEMBL3953119 | — | — | 3 | 8.06 |
| CHEMBL6049272 | — | — | 3 | 8.00 |
| CHEMBL4466302 | — | — | 3 | 7.99 |
| CHEMBL5891847 | — | — | 3 | 7.94 |
| CHEMBL5803160 | — | — | 3 | 7.93 |
| CHEMBL5976681 | — | — | 3 | 7.93 |
| CHEMBL6061610 | — | — | 3 | 7.91 |
| CHEMBL3953069 | — | — | 3 | 7.86 |
| CHEMBL5822647 | — | — | 3 | 7.74 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL119 | TRIMETREXATE | IC50 | = | 1.35 | nM | 8.87 |
| CHEMBL5941951 | — | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL4468777 | FANOTAPRIM | IC50 | = | 3.24 | nM | 8.49 |
| CHEMBL5936551 | — | IC50 | = | 3.47 | nM | 8.46 |
| CHEMBL5985430 | — | IC50 | = | 3.89 | nM | 8.41 |
| CHEMBL5751279 | — | IC50 | = | 4.17 | nM | 8.38 |
| CHEMBL5796794 | — | IC50 | = | 4.37 | nM | 8.36 |
| CHEMBL4543226 | — | IC50 | = | 4.47 | nM | 8.35 |
| CHEMBL4573445 | — | IC50 | = | 4.79 | nM | 8.32 |
| CHEMBL6034917 | — | IC50 | = | 5.62 | nM | 8.25 |
| CHEMBL5883668 | — | IC50 | = | 5.75 | nM | 8.24 |
| CHEMBL5877082 | — | IC50 | = | 5.89 | nM | 8.23 |
| CHEMBL4464707 | — | IC50 | = | 6.03 | nM | 8.22 |
| CHEMBL5806347 | — | IC50 | = | 6.17 | nM | 8.21 |
| CHEMBL5830010 | — | IC50 | = | 6.17 | nM | 8.21 |
| CHEMBL5831279 | — | IC50 | = | 6.46 | nM | 8.19 |
| CHEMBL6014553 | — | IC50 | = | 6.76 | nM | 8.17 |
| CHEMBL6001741 | — | IC50 | = | 6.92 | nM | 8.16 |
| CHEMBL5806112 | — | IC50 | = | 7.24 | nM | 8.14 |
| CHEMBL5759188 | — | IC50 | = | 7.24 | nM | 8.14 |
| CHEMBL5857341 | — | IC50 | = | 8.13 | nM | 8.09 |
| CHEMBL3953119 | — | IC50 | = | 8.71 | nM | 8.06 |
| CHEMBL6049272 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL4466302 | — | IC50 | = | 10.2 | nM | 7.99 |
| CHEMBL5891847 | — | IC50 | = | 11.5 | nM | 7.94 |
| CHEMBL5976681 | — | IC50 | = | 11.7 | nM | 7.93 |
| CHEMBL5803160 | — | IC50 | = | 11.7 | nM | 7.93 |
| CHEMBL6061610 | — | IC50 | = | 12.3 | nM | 7.91 |
| CHEMBL3953069 | — | IC50 | = | 13.8 | nM | 7.86 |
| CHEMBL5822647 | — | IC50 | = | 18.2 | nM | 7.74 |
| CHEMBL5796711 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL5856822 | — | IC50 | = | 25.7 | nM | 7.59 |
| CHEMBL5777305 | — | IC50 | = | 26.3 | nM | 7.58 |
| CHEMBL5975024 | — | IC50 | = | 27.5 | nM | 7.56 |
| CHEMBL4584470 | — | IC50 | = | 27.5 | nM | 7.56 |
| CHEMBL4435247 | — | IC50 | = | 28.8 | nM | 7.54 |
| CHEMBL4544467 | — | IC50 | = | 30.9 | nM | 7.51 |
| CHEMBL5747929 | — | IC50 | = | 33.1 | nM | 7.48 |
| CHEMBL5786336 | — | IC50 | = | 34.7 | nM | 7.46 |
| CHEMBL4456834 | — | IC50 | = | 45.7 | nM | 7.34 |
| CHEMBL4535103 | — | IC50 | = | 61.7 | nM | 7.21 |
| CHEMBL6013215 | — | IC50 | = | 70.8 | nM | 7.15 |
| CHEMBL4549054 | — | IC50 | = | 75.9 | nM | 7.12 |
| CHEMBL34259 | METHOTREXATE | IC50 | = | 77.6 | nM | 7.11 |
| CHEMBL5783758 | — | IC50 | = | 138.0 | nM | 6.86 |
| CHEMBL5985260 | — | IC50 | = | 138.0 | nM | 6.86 |
| CHEMBL5939499 | — | IC50 | = | 162.0 | nM | 6.79 |
| CHEMBL4553229 | — | IC50 | = | 209.0 | nM | 6.68 |
| CHEMBL5779683 | — | IC50 | = | 269.0 | nM | 6.57 |
| CHEMBL36 | PYRIMETHAMINE | IC50 | = | 275.0 | nM | 6.56 |