Assay Detail
Functional
CHEMBL615276
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Antiviral activity against Hepatitis B virus in 2.2.15 cell line
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Anti-human immunodeficiency and anti-hepatitis B virus activities of -l-2,3-dideoxy purine nucleosides
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 5.57 | 5.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL290427 | — | — | 1 | 5.92 |
| CHEMBL23094 | — | — | 1 | 5.22 |
| CHEMBL78101 | — | — | 1 | - |
| CHEMBL45254 | — | — | 1 | - |
| CHEMBL45071 | — | — | 1 | - |
| CHEMBL1460 | DIDANOSINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL290427 | — | EC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL23094 | — | EC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL78101 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL45254 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL45071 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL1460 | DIDANOSINE | EC50 | > | 10000.0 | nM | - |