Assay Detail
Functional
CHEMBL615277
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro effective concentration against hepatitis B virus was determined in 2.2.15 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis, anti-human immunodeficiency virus and anti-hepatitis B virus activities of novel oxaselenolane nucleosides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.65 | 8.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL141 | LAMIVUDINE | 4.0 | 1 | 8.10 |
| CHEMBL433859 | — | — | 1 | 5.92 |
| CHEMBL127637 | — | — | 1 | 5.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL141 | LAMIVUDINE | EC50 | = | 8.0 | nM | 8.10 |
| CHEMBL433859 | — | EC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL127637 | — | EC50 | = | 1200.0 | nM | 5.92 |