Assay Detail
Functional
CHEMBL615297
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Inhibitory concentration by single cycle replication assay using envelope deficient HIV-1
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Structure activity of 3-aryl-1,3-diketo-containing compounds as HIV-1 integrase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.93 | 6.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL108253 | — | — | 1 | 6.22 |
| CHEMBL320261 | — | — | 1 | 5.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL108253 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL320261 | — | IC50 | = | 2300.0 | nM | 5.64 |