Assay Detail
Binding
CHEMBL615411
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Inhibition constant against 3-dehydroquinate synthase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
The basis for slowly reversible inhibition of dehydroquinate synthase: a case of mistaken identity?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.07 | 8.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL281425 | — | — | 1 | 8.27 |
| CHEMBL26862 | — | — | 1 | 6.66 |
| CHEMBL29553 | — | — | 1 | 6.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL281425 | — | Ki | = | 5.4 | nM | 8.27 |
| CHEMBL26862 | — | Ki | = | 220.0 | nM | 6.66 |
| CHEMBL29553 | — | Ki | = | 540.0 | nM | 6.27 |