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Assay Detail

CHEMBL615641

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was tested for the inhibitory activity of compound towards human rhinovirus 3C protease
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Enterovirus
Confidence 1 — Organism
Curated By Intermediate

Target

Enterovirus (CHEMBL613749)
Type ORGANISM
Organism Enterovirus

Publication

Design, synthesis, and evaluation of nonpeptidic inhibitors of human rhinovirus 3C protease.
Webber SE, Tikhe J, Worland ST, Fuhrman SA, Hendrickson TF, Matthews DA, Love RA, Patick AK, Meador JW, Ferre RA, Brown EL, DeLisle DM, Ford CE, Binford SL.
J Med Chem (1996) 39 : 5072 -5082
PubMed 8978838 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 3 7.98 8.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL149950 1 8.70
CHEMBL150011 1 7.96
CHEMBL148483 1 7.29

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL149950 Ki = 2.0 nM 8.70
CHEMBL150011 Ki = 11.0 nM 7.96
CHEMBL148483 Ki = 51.0 nM 7.29