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Assay Detail

CHEMBL616532

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Binding
Binding affinity was evaluated at the cloned human 5-hydroxytryptamine 1B receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 1B (CHEMBL1898)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

3-(2-pyrrolidin-1-ylethyl)-5-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole derivatives as high affinity human 5-HT(1B/1D) ligands.
Egle I, MacLean N, Demchyshyn L, Edwards L, Slassi A, Tehim A.
Bioorg Med Chem Lett (2004) 14 : 727 -729
PubMed 14741277 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.21 6.21

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL115415 1 6.21

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL115415 Ki = 610.0 nM 6.21