Assay Detail
Binding
CHEMBL616724
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Binding affinity against 5-hydroxytryptamine 1F receptor in CHO cells using [3H]5-HT radioligand
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | CHO |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
N-Arylsulfonylindole derivatives as serotonin 5-HT(6) receptor ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 6.57 | 8.41 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL92139 | — | — | 1 | 8.41 |
| CHEMBL125745 | — | — | 1 | 7.33 |
| CHEMBL126340 | — | — | 1 | 6.24 |
| CHEMBL93868 | — | — | 1 | 6.11 |
| CHEMBL317535 | — | — | 1 | 5.70 |
| CHEMBL76237 | — | — | 1 | 5.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL92139 | — | Ki | = | 3.9 | nM | 8.41 |
| CHEMBL125745 | — | Ki | = | 47.0 | nM | 7.33 |
| CHEMBL126340 | — | Ki | = | 570.0 | nM | 6.24 |
| CHEMBL93868 | — | Ki | = | 770.0 | nM | 6.11 |
| CHEMBL317535 | — | Ki | = | 2000.0 | nM | 5.70 |
| CHEMBL76237 | — | Ki | = | 2500.0 | nM | 5.60 |