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Assay Detail

CHEMBL616804

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was evaluated for the binding affinity towards 5-hydroxytryptamine 1B receptor by displacement of [3H]ketanserin.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 1B (CHEMBL1898)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthesis, biological activity and quantitative structure-activity relationships of N-substituted-3,4-dihydro-2H-1-benzopyran derivatives
Marot C, Comoy C, Viaud M, Rettori M, Pfeiffer B, Morin-Allory L, Guillaumet G
Bioorg Med Chem Lett (1996) 6 : 1077 -1082
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.18 5.18

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL11265 1 5.18

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL11265 IC50 = 6606.93 nM 5.18