Assay Detail
Binding
CHEMBL616886
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was evaluated for displacement of [3H]ketanserin from human cloned 5-hydroxytryptamine 2A receptor in transfected CHO-K1 cells
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | CHO-K1 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Some benzenesulfonamido-substituted valerophenones that are selective antagonists for the 5-HT2C receptor
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 7.68 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL93862 | — | — | 1 | 9.00 |
| CHEMBL91221 | — | — | 1 | 8.20 |
| CHEMBL90346 | — | — | 1 | 7.90 |
| CHEMBL310656 | — | — | 1 | 7.70 |
| CHEMBL90470 | — | — | 1 | 6.90 |
| CHEMBL432217 | — | — | 1 | 6.40 |
| CHEMBL90509 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL93862 | — | Ki | = | 1.0 | nM | 9.00 |
| CHEMBL91221 | — | Ki | = | 6.31 | nM | 8.20 |
| CHEMBL90346 | — | Ki | = | 12.59 | nM | 7.90 |
| CHEMBL310656 | — | Ki | = | 19.95 | nM | 7.70 |
| CHEMBL90470 | — | Ki | = | 125.89 | nM | 6.90 |
| CHEMBL432217 | — | Ki | = | 398.11 | nM | 6.40 |
| CHEMBL90509 | — | Ki | < | 10000.0 | nM | - |