Assay Detail
Binding
CHEMBL616891
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibitory constant for human 5-hydroxytryptamine 2A receptor transfected in to CHO cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
New serotonin 5-HT(2A), 5-HT(2B), and 5-HT(2C) receptor antagonists: synthesis, pharmacology, 3D-QSAR, and molecular modeling of (aminoalkyl)benzo and heterocycloalkanones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 8.05 | 9.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL164471 | — | — | 1 | 9.14 |
| CHEMBL333174 | — | — | 1 | 8.93 |
| CHEMBL95098 | — | — | 1 | 7.17 |
| CHEMBL310734 | — | — | 1 | 6.94 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL164471 | — | Ki | = | 0.7244 | nM | 9.14 |
| CHEMBL333174 | — | Ki | = | 1.175 | nM | 8.93 |
| CHEMBL95098 | — | Ki | = | 67.61 | nM | 7.17 |
| CHEMBL310734 | — | Ki | = | 114.82 | nM | 6.94 |